Alicalcil 60caps - MJS Med

Alicalcil 60caps - MJS Med

Alicalcil® from MJS MED is a supplement that contributes to the prevention and treatment of osteoporosis.

Calcium has been shown to be more effective than a placebo in clinical trials, with a reduction in bone loss rates observed after 2 weeks of treatment. Furthermore, the risk of vertebral fracture is reduced by approximately 21%, compared to 14% for non-vertebral fracture. There is a close relationship between pre-menopausal bone density and the risk of osteoporosis. Due to this, the formation of strong bone tissue should be a lifelong goal, starting early in childhood. Calcium supplementation during menopause is fundamental for prevention. Calcium phosphate meets the requirements for a chelating agent: it is easily ionizable, almost completely degraded, has virtually no apparent toxicity, and increases the absorption of other minerals.

Magnesium (in the form of Bisglycinate) can be as important as calcium administration for the prevention and treatment of osteoporosis. Magnesium deficiency in inferior bone is primarily associated with a decrease in the serum concentration of the most active form of vitamin D3. Mechanism: the enzymes responsible for the conversion of 25-(OH)D3 to 1,25-(OH)2D3 are magnesium-dependent, or rather, it intervenes in the mediation of PTH and calcitonin.

Silicon is necessary for the establishment of cross-links between collagen bands and for reinforcing the integrity of the bone connective tissue matrix. Silicon levels increase in areas of bone calcification during the growth phase. In patients with osteoporosis and in situations where bone regeneration is desired, silicon intake can be increased according to needs.

Boron is a trace element that induces a protective effect against osteoporosis. Administration of 3 mg/day in post-menopausal women reduces urinary calcium excretion by 44% and significantly increases concentrations of 17-beta-estradiol, the estrogen with the highest biological activity. It is necessary to activate certain hormones (e.g., estrogens) and vitamin D. It is also necessary to convert vitamin D into its active form in the kidneys.

Vitamin D3 stimulates calcium absorption. It is synthesized by the effect of sunlight on 7-dehydrocholesterol in the skin. Sunlight converts this into vitamin D3 (cholecalciferol). The liver converts it into 25-(OH)D3, which is five times more potent than cholecalciferol. 25-hydroxycholecalciferol is converted into 1,25-(OH)2D3, which is 10 times more potent than vitamin D3. Liver and kidney pathologies alter this conversion. Some patients with osteoporosis show high concentrations of 25-(OH)D3 but low concentrations of 1,25-(OH)2D3, which indicates that they suffer from some kidney disorder. The addition of boron to the formulation performs the function of renal conversion. The administration of 700 IU of vitamin D3 decreases the annual incidence of hip fractures by 60%. The combination of vitamin D3 and calcium yields optimized results.

Pack of 60 capsules - oral